Scott grew up in Indianapolis, Indiana. He graduated from Taylor University in Upland, Indiana, and then served on the staff of U.S. Senator Richard Lugar for nearly six years. Having sensed a call to full-time Christian service, he moved to Kenya in 1993 where he began supporting the work of Samaritan’s Purse, first in Kenya and Somalia, and then throughout Africa. Scott implemented and supported projects and programs across the spectrum of sectors and with many ministry partners. Although he has traveled extensively throughout Africa, he was especially involved in Kenya, Uganda, Ethiopia, Eritrea, South Sudan, and Rwanda. His work eventually took him regularly to Egypt and the Middle East. In 2010, he left Kenya to serve in the Kingdom of Jordan where he led the Annoor Sanatorium for Chest Diseases.

Scott now resides in Boone, North Carolina, where he continues to oversee the Annoor Sanatorium in Jordan and leads World Medical Mission, a medical ministry of Samaritan's Purse. Scott is married to Trish and they have two teenage daughters, Sophie and Sadie.